WE ARE COMMITTED TO BRING YOU COVID-19 AND SARS-CoV-2 SCIENTIFIC UPDATES
See also the South African Government Resource: sacoronavirus.co.za
13th August
Using a humanized mouse model and B cells from COVID-19 convalescent individuals, Hansen et al., describe the discovery of two SARS-CoV2-specific antibodies: REGN10933 and REGN10987 that are currently being tested for immunotherapeutic potential against COVID-19 (NCT04426695; NCT04425629). Both antibodies non-competitively bind to SARS-CoV-2 receptor binding domain… Read More…
12th August
Based on the heterogeneity of COVID-19 pathology, Sacha and colleagues hypothesised that cytokines such as IL-6, IL-8, IL-1β and TNF could potentially predict disease severity and outcome. Sacha demonstrated that IL-6, IL-8 and TNF, individually and when combined in a model, correlate with various aspects of disease severity and survival outcome. Based on these results, targeting these cytokines… Read More…
Effective host immune responses are required for optimum viral control. Immune reactions to a viral threat, on the contrary, could also be harmful to the host if the response is excessive. Huang et al. noted that upon infection with Covid-19, the initial levels of inflammatory cytokines e.g. IL1β were higher… Read More…
August 2020
Dr Jude Uzonna, Professor of Immunology is currently the Associate Dean (Research) at the Max Rady College of Medicinem University of Manitoba. Watch our 4 part interview of Prof. Uzonna that discusses his own research on trypanosomiasis, future of research in Africa and advice for future scientist Read More…
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